Podcast Episodes

Scroll through our episodes below and click to learn more about the episode, link to the video or link to the podcast on Apple Podcasts or Spotify. You can also narrow results by clicking on any tag.

83: Sexually Transmitted Cancer

83: Sexually Transmitted Cancer

Buck Joffrey, MD reviews what is known about sexually transmitted cancers. Discussion includes HIV and Hepatitis but focuses on Human...

82: Intro to the Microbiome

82: Intro to the Microbiome

Buck Joffrey, MD provides an introduction to the microbiome and discusses its importance. Topics also include prebiotics, probiotics,...

81: Ask the Doctor 04/29/24

81: Ask the Doctor 04/29/24

Buck Joffrey, MD, takes questions from the audience. Topics include human growth hormones, the potentially harmful effects of an MN, 40...

80: The Longevity Diet with Valter Longo, PhD

80: The Longevity Diet with Valter Longo, PhD

Buck Joffrey, MD, discusses the fasting regimen with Dr. Valter Longo, PhD. Dr. Longo is a world, renowned researcher in longevity and...

79: Lies Taught in Medical School: Robert Lufkin, M.D.

79: Lies Taught in Medical School: Robert Lufkin, M.D.

Buck Joffrey, MD interviews Robert Lufkin, MD about his book Lies I Taught in Medical School: And the Truths That Can Save Your...

78: The Age of Data Driven Wellness is Here

78: The Age of Data Driven Wellness is Here

Dr. Buck Joffrey, M.D. interviews, Dr. Nathan Price, PhD from Thorne about a new paradigm in medicine driven by data, technology, and...

76: Intermittent Fasting Correlated to Higher Risk of Cardiovascular Death

76: Intermittent Fasting Correlated to Higher Risk of Cardiovascular Death

In this episode of Sapio, Dr. Buck Joffrey, MD addresses the recent American Heart Association study correlating intermittent...

75: Stress, Cortisol, and Prevention Strategies

75: Stress, Cortisol, and Prevention Strategies

Buck Joffrey, MD talks to Romie Mushtaq, MD regarding stress, cortisol levels and prevention strategies including meditation and...

74: Aggressive Male TRT Approach,  Erectile Dysfunction Drugs, and Alzheimer’s Disease

74: Aggressive Male TRT Approach, Erectile Dysfunction Drugs, and Alzheimer’s Disease

Buck Joffrey MD speaks to Justin Houman MD who is a urologist regarding the idea of aggressive testosterone treatment to decrease the...

73: Is a Vegan Diet Healthy?

73: Is a Vegan Diet Healthy?

Buck Joffrey, MD and Linda Tyler, PhD discuss the topic of plant-based only/Vegan diets. The conversation includes topics on...

72: A Different Framework for Health?

72: A Different Framework for Health?

Buck Joffrey, MD interviews Anoop Kumar, MD on his perspective on health and wellness. Dr. Kumar is an emergency medicine doctor who is...

71: Ask the Doctor 02/19

71: Ask the Doctor 02/19

In this episode, Buck addresses questions from listeners. Topics include:

00:34 What is a healthy range in your...

70: The Science Behind Music and Mental Health

70: The Science Behind Music and Mental Health

Buck Joffrey, MD interviews Dr. Daniel Bowling from Stanford University on the science behind music and...

69: Glutathione: The Master Antioxidant

69: Glutathione: The Master Antioxidant

Buck Joffrey, MD welcomes pharmacist and glutathione expert Dr. Nayan Patel. This podcast discusses the role of glutathione as an...

68: Food Allergy 101 with Tina Sindher, MD

68: Food Allergy 101 with Tina Sindher, MD

Buck welcomes Tina Sindher, a specialist in food allergy from Stanford University Medical Center to discuss the basics of food...

67: The Silent Global Epidemic Killer

67: The Silent Global Epidemic Killer

Buck Joffrey, M.D. discusses metabolic syndrome which affects 1/4 of the global adult population and how it underlies the development of...

66: What is the common cold and how do you treat it?

66: What is the common cold and how do you treat it?

Buck talks about the common cold. He discusses the etiology, the role of cold weather, prevention and treatment of this common and...

65: Aging Skin and How to Fight It

65: Aging Skin and How to Fight It

Buck interviews Dr. Corey Frucht, MD, PhD, a board-certified dermatologist on the topic of aging skin and skin cancer. This episode...

63: A Look Back at 2023

63: A Look Back at 2023

In this special New Year episode, Buck reviews some of the concepts discussed on the show in 2023.

62: Ask the Doctor 12/23

62: Ask the Doctor 12/23

In this episode, Buck addresses questions from listeners. Topics include oral hygiene, Alzheimer’s disease, and Matthew...

61: Wisdom Wednesday: Surviving vs Winning

61: Wisdom Wednesday: Surviving vs Winning

Buck talks about mindset and the self-inflicted limits of the “survivor.”

60: Inflammaging

60: Inflammaging

Buck Joffrey, MD summarizes his literature search on what the data says in regards to the mechanisms by which the most common diseases...

59: How Much Exercise Is Too Much For Longevity?

59: How Much Exercise Is Too Much For Longevity?

In this brief video, Buck Joffrey discusses literature suggesting that there is a "Goldilocks" zone for exercising for longevity. He...

58: A Review on the Risks and Benefits of Human Growth Hormone Supplementation

58: A Review on the Risks and Benefits of Human Growth Hormone Supplementation

Buck reviews the physiology behind human growth and hormones in humans. He discusses normal growth hormone patterns as people age,...

57: How Stress Impacts Your Body

57: How Stress Impacts Your Body

Stress is an unavoidable element in modern society. Inherently, We know it’s bad for us. In this episode of Sapio, Buck looks at...

56: Ask the Doctor (December 2023)

56: Ask the Doctor (December 2023)

In this episode of Sapio with Buck Joffrey, Buck welcomes back Dr. Alan Viglione of Montecito Concierge Medicine. Dr. Viglone discuss...

55: Engaging Your Subconscious For Success

55: Engaging Your Subconscious For Success

In this episode of Sapio with Buck Joffrey, Buck discusses the importance of setting clear goals and truly believing they can be...

54: What Supplements Does Buck Take?

54: What Supplements Does Buck Take?

In this episode of Sapio with Buck Joffrey, Buck reveals the supplements and drugs that he takes for the purpose of longevity. In...

53: How to Avoid Blood Clots During Holiday Travel

53: How to Avoid Blood Clots During Holiday Travel

Buck provides ways to prevent getting deep venous thrombosis during long flights and drives. Deep Venous thrombosis refers to clots in...

52: What You Need to Know About Protein and Longevity

52: What You Need to Know About Protein and Longevity

In this episode of Sapio, Buck drills down on the importance of adequate levels of protein in a diet designed for longevity.

Buck...

51: Part 2 - Alzheimers’s Disease - Risk Factors, Prevention and Treatment

51: Part 2 - Alzheimers’s Disease - Risk Factors, Prevention and Treatment

In our last episode of Sapio with Buck Joffrey, Neurologist Dr. John Foley took us through the diagnosis and pathophysiology behind...

50: Part 1 - Alzheimers’s Disease: Risk Factors, Prevention and Treatment

50: Part 1 - Alzheimers’s Disease: Risk Factors, Prevention and Treatment

In the next two episodes of Sapio with Buck Joffrey, we are going to talk about Alzheimer’s disease.

If you have never seen...

49: 3 Eating Tips to Live Longer

49: 3 Eating Tips to Live Longer

Buck offers three quick tips on eating to live longer.

48: Living Longer for Busy People

48: Living Longer for Busy People

Buck discusses his new book Living Longer for Busy People with Executive Producer Ben Hyatt.

47: Exercising for Longevity and More with Dr. Tom Walters | 2 of 2

47: Exercising for Longevity and More with Dr. Tom Walters | 2 of 2

Sapio with Buck Joffrey Episode 47 is part 2 of a 2 part episode with Dr. Tom Walters, DPT, OCS. Tom is a Doctor of Physical Therapy,...

46: Exercising for Longevity and More with Dr. Tom Walters | 1 of 2

46: Exercising for Longevity and More with Dr. Tom Walters | 1 of 2

Sapio with Buck Joffrey Episode 46 is part 1 of a 2 part episode with Dr. Tom Walters, DPT, OCS. Tom is a Doctor of Physical Therapy,...

45: WHEN to Sleep to Reduce Your Risk of Alzheimer's Disease

45: WHEN to Sleep to Reduce Your Risk of Alzheimer's Disease

It's not just how much you sleep but WHEN you sleep that can affect your chances of getting Alzheimer's Disease. Buck Explains.

44: This Old Gout Drug May Help You Live Longer

44: This Old Gout Drug May Help You Live Longer

In Episode 44 of Sapio with Buck Joffrey, Buck discusses research that shows this old drug can be repurposed to fight the number one...

43: Make This One Simple Change To Improve Your Sleep

43: Make This One Simple Change To Improve Your Sleep

In this Medical Update, Buck talks about one quick thing you can do to significantly improve the quality of your sleep. It goes against...

42: Ask The Doctor

42: Ask The Doctor

In our latest "Ask The Doctor" episode, Dr. Alan Viglione joins Buck for a conversation that includes how to find a doctor that's right...

41: FDA Panel: Popular Cold Medicine Doesn't Work

41: FDA Panel: Popular Cold Medicine Doesn't Work

In this medical update Buck discusses news from the FDA about some of the most popular drugs at your pharmacy. Buck also discusses some...

40: Full Body MRI: Avoiding Health Time Bombs

40: Full Body MRI: Avoiding Health Time Bombs

In this Sapio with Buck Joffrey episode Buck talks to Dr. Sean London from Prenuvo. A company revolutionizing healthcare with it's full...

38: What is your TRUE age? Biological VS Chronological

38: What is your TRUE age? Biological VS Chronological

In this Sapio with Buck Joffrey Episode Short, Buck discusses Biological Age and how it is different than Chronological Age. Which of...

37:  Psilocybin: Evidence that a Psychedelic May Treat Depression

37: Psilocybin: Evidence that a Psychedelic May Treat Depression

In this Sapio with Buck Joffrey Medical Update, Buck discusses depression and the psychedelics being used to treat it including...

35: Is Hearing Loss Connected to Dementia?

35: Is Hearing Loss Connected to Dementia?

In this Sapio with Buck Joffrey Medical Update, Buck discusses new reasearch that connects hearing loss and dementia. If you or a loved...

34: Female Sexual Dysfunction

34: Female Sexual Dysfunction

In this episode of Sapio with Buck Joffrey Dr. Duncan Turner joins Buck for a conversation on women's health, sexual dysfunction and...

33: The Cutting Edge Science of Age Reversal - Part 2

33: The Cutting Edge Science of Age Reversal - Part 2

The exploration into the secrets of aging continues in this much-anticipated second part of our conversation with Dr. Joel Rothman from...

32: The Cutting Edge Science of Age Reversal - Part 1

32: The Cutting Edge Science of Age Reversal - Part 1

In this can't-miss episode, Buck engages in a riveting conversation with the Dr. Joel Rothman, the Founding Director at UCSB's Center...

Sapio Episode 31: What Covid Does To Your Brain

Sapio Episode 31: What Covid Does To Your Brain

Episode 31 of Sapio with Buck Joffrey discusses "What Covid does to your Brain". In this short episode Buck discusses his personal...

31: What Covid does to your Brain

31: What Covid does to your Brain

Episode 31 of Sapio with Buck Joffrey discusses "What Covid does to your Brain". In this short episode Buck discusses his personal...

Sapio Episode 30: What’s Your Risk of Getting Alzheimer’s Disease?

Sapio Episode 30: What’s Your Risk of Getting Alzheimer’s Disease?

In this episode of Sapio with Buck Joffrey, Buck discusses a new study out of Oxford that outlines 11 key risk factors for dementia. And...

30: What’s Your Risk of Getting Alzheimer’s Disease?

30: What’s Your Risk of Getting Alzheimer’s Disease?

In this episode of Sapio with Buck Joffrey, Buck discusses a new study out of Oxford that outlines 11 key risk factors for dementia. And...

29: Male Sexual Health - Part 2

29: Male Sexual Health - Part 2

In part 2 of this 2 part episode Buck discusses male sexual health with Justin Houman, MD from Tower Urology in Los Angeles. Over half...

28: Male Sexual Health - Part 1

28: Male Sexual Health - Part 1

In this two part episode Buck discusses male sexual health with Justin Houman, MD from Tower Urology in Los Angeles. Over half of...

27: Yamanaka Factors - Can Aging Be Reversed?

27: Yamanaka Factors - Can Aging Be Reversed?

Buck discusses Yamanaka Factors and recent experiments where a team led by David Sinclair was successful in reversing cellular age...

26: Ask The Doctor P2 of 2

26: Ask The Doctor P2 of 2

In this edition of Ask The Doctor Executive Producer asks Buck viewer questions and some of his own. Discussed is continuous glucose...

25: Heart Rate Variability (HRV)

25: Heart Rate Variability (HRV)

Buck discusses Heart Rate Variability (HRV). What is it? Why does it matter and how can it effect your overall health in this mini Sapio...

24: Ask The Doctor P1 of 2

24: Ask The Doctor P1 of 2

In this edition of Ask The Doctor Executive Producer asks Buck viewer questions and some of his own. Discussed is continuous glucose...

23: Jet Lag and Melatonin

23: Jet Lag and Melatonin

Planning a trip? Jet lag can be a serious impediment to making the most of it. Buck discusses jet lag; what it is and strategies to beat...

22: Battle of Cardio IQs Part 2

22: Battle of Cardio IQs Part 2

Buck and Alan Viglione, MD discuss the Cardio IQ® report in detail and battle it out to see has the best numbers in this 2 part...

21: Why Did Bronny James Collapse?

21: Why Did Bronny James Collapse?

Scary news last week when Bronny James, the 18 year old son of Lebron and Savannah James collapsed during a workout at USC. It has been...

20: Battle of Cardio IQs Part 1

20: Battle of Cardio IQs Part 1

Buck and Alan Viglione, MD discuss the Cardio IQ® report in detail and battle it out to see has the best numbers in this 2 part...

19: Snoring and Sleep Apnea: Just Noise or Silent Killers?

19: Snoring and Sleep Apnea: Just Noise or Silent Killers?

In this episode Buck discusses snoring and sleep apnea and why they should be taken seriously.

  • 0:01:17 - Snoring And Sleep...

18: Could This Simple Blood Test Revolutionize Early Cancer Detection?

18: Could This Simple Blood Test Revolutionize Early Cancer Detection?

Buck talks with GRAIL President Josh Ofman, MD, MSHS, about their groundbreaking Multi-cancer early detection (MCED) technology and it's...

17: Is Your Diet Coke Killing You?

17: Is Your Diet Coke Killing You?

In this Sapio Short Buck discusses the news last week that the World Health Organization (WHO) has declared the artificial sweetener...

16: Ask the Doctor

16: Ask the Doctor

In this episode, Alan Viglione, MD joins Buck to answer some of our audience questions.

  • 0:01:08 - How To Prevent The Dawn...

15: Essentials of Female Hormone Replacement

15: Essentials of Female Hormone Replacement

In this episode Buck continues his conversation with Rob Hamilton MD from Prestige Regenerative Medicine - this time discussing Female...

14: Essentials of Male Hormone Replacement

14: Essentials of Male Hormone Replacement

Buck discusses Male Hormone Replacement with Rob Hamilton, MD from Prestige Regenerative Medicine. When to get it, why to get it, what...

13: Reprogramming Your Brain with Ketamine and Psychedelics: Part 2

13: Reprogramming Your Brain with Ketamine and Psychedelics: Part 2

In part two of a two part episode Buck talks with Dr. Michael Mantz, MD about Ketamine and Psychedlics.

  • 0:00:29 - What Is...

12: Reprogramming Your Brain with Ketamine and Psychedelics: Part 1

12: Reprogramming Your Brain with Ketamine and Psychedelics: Part 1

In this is a two part episode Buck talks with Dr. Michael Mantz, MD about Ketamine and Psychedlics. Part 2 will be online for our...

11: Fountain of Youth or Just a Dry Sauna?

11: Fountain of Youth or Just a Dry Sauna?

Buck discusses studies on the effect of saunas for overall health and longevity.

  • 0:01:35 - What's The Big Deal With...

10: Longevity Pillar 6: Being Social Helps You Live Longer

10: Longevity Pillar 6: Being Social Helps You Live Longer

Buck and Montecito Concierge Medicine’s Alan Viglione explore compelling studies revealing the profound impact of social connections...

9: Taurine: An Ingredient in Energy Drinks that May Add Years to Your Life!

9: Taurine: An Ingredient in Energy Drinks that May Add Years to Your Life!

Buck discusses with Executive Producer Ben Hyatt a study that appeared June 9th, 2023 in Science magazine that linked Taurine with...

8: Longevity Pillar 5: Personalized Diagnostics to Monitor Your Own Health

8: Longevity Pillar 5: Personalized Diagnostics to Monitor Your Own Health

Shownotes:

  • 1:02 What is Diagnostics when it comes to medicine?
  • 2:35 What are some of the traditional Diagnostics...

7: Metformin: Miracle Longevity Drug or Hype?

7: Metformin: Miracle Longevity Drug or Hype?

Shownotes:

  • 0:01:04 Metformin and Diabetes
  • 0:02:48 Metformin Monotherapy
  • 0:06:46 Are There Any...

6: Longevity Pillar 4: Taking Drugs That Can Help You Live Longer

6: Longevity Pillar 4: Taking Drugs That Can Help You Live Longer

Shownotes:

  • 0:01:54 Geroprotective Medication
  • 0:09:51 Addressing Fear Of Medication
  • 0:12:22 Preventing...

5: Longevity Pillar 3: Sleeping to Live Longer and Healthier

5: Longevity Pillar 3: Sleeping to Live Longer and Healthier

Shownotes:

  • 0:01:31 The Importance Of Sleep For Health
  • 0:03:41 Rapid Eye Movement (REM) Sleep
  • 0:03:57...

4: Longevity Pillar 2: Exercise THE RIGHT WAY!

4: Longevity Pillar 2: Exercise THE RIGHT WAY!

Our understanding of how to get the most out of exercise has evolved. A combination of cardio training with weight training can have a...

3: Why Hyperglycemia is a KILLER (and what to do about it)

3: Why Hyperglycemia is a KILLER (and what to do about it)

In this bonus Q&A episode Buck Joffrey dives a little deaper into one of the key Episode 2 topics - blood glucose and how it affects...

2: Longevity Pillar 1: What to Eat and When

2: Longevity Pillar 1: What to Eat and When

There is more to healthy eating than calories in and calories out. Learn the new science around eating to extend life including what to...

1: An Introduction to Sapio

1: An Introduction to Sapio

An Introduction to the pillars on longevity and underlying science. Buck talks with Montecito Concierge Medicine’s Alan...